Heart mitral valve disease (MVD) is a terminal illness which may afflict over half of all cavalier King Charles spaniels by the age of 5 years and nearly all Cavaliers by age 10 years. It is CKCSs' leading cause of death.
- More: Cavalier King Charles spaniel MVD
- Mitral valve disease breeding protocol
- A few words about pimobendan (Vetmedin)
- ACVIM cardiologists consensus statement
- Research news
- Find a cardiologist in the USA and Canada
- October 2015 - Dutch researchers determine that the optimum time for daily doses of ACE-inhibitors to dogs in congestive heart failure is expected to be at bedtime.
- October 2015 - UK researchers find anti-epileptic properties in ketogenic diets reduce seizure frequencies in epileptic dogs.
- September 2015 - Belgian researchers find the pulmonary-vein-to-pulmonary-artery ratio increases with severity of MVD.
- September 2015 - Swedish researchers find echocardiographic variables that can identify pulmonary hypertension in dogs with MVD.
- September 2015 - Tufts researchers find possible cardiac cachexia preventative is well tolerated by dogs in congestive heart failure.
- September 2015 - Japanese cardiologists find overdose of pimobendan accelerates progression of MVD.
- September 2015 - Italian researchers find retinal dysplasia and microphthalmia in a family of CKCSs.
- September 2015 - International Veterinary Epilepsy Task Force reports on epilepsy in cavaliers.
- September 2015 - International Veterinary Epilepsy Task Force issues a consensus proposal on diagnosing idiopathic epilepsy.
- September 2015 - International Veterinary Epilepsy Task Force reports on myoclonus in cavaliers.
- September 2015 - UK researchers report mixed results of tympanostomy tube treatment for PSOM in cavaliers.
- September 2015 - International team of cardiologists and nephrologists issue a Consensus Statement on cardio-renal disorders.
- September 2015 - Study of healthy dogs finds enalapril suppresses ACE activity but does not suppress circulating RAAS.
- August 2015 - Japanese researchers find that vitamin D concentration declines with the progression of MVD in dogs, including cavaliers.
- August 2015 - Thai researchers find plasma Galectin-3 increases with cardiac fibrosis in MVD-affected dogs.
- August 2015 - Statistical analysis of MRI-scanned asymptomatic cavaliers show that the presence of a syrinx is a risk factor for later development of clinical signs of CM/SM.
- August 2015 - Cerebellar infarction symptoms in cavaliers resemble acute vestibular signs.
- August 2015 - Japanese researchers find a congenital cerebral cavity, porencephaly, in a fly-biting cavalier.
- August 2015 - Extreme beta-cell deficiency is noted in diabetic dogs.
- August 2015 - Study of MVD-affected dogs shows a progressive inflammatory component.
- August 2015 - UK neurologist seeks CM/SM-affected cavaliers for non-invasive pain assessment study.
- August 2015 - US vet reports a case of eosinophilic stomatitis in a cavalier.
- August 2015 - Dutch study finds post-operative reoccurrence of cherry eye is linked to other eye disorders.
- August 2015 - UK researchers compare anti-convulsants gabapentin and topiramate in a study of 33 cavaliers with CM/SM.
- August 2015 - UK research points to gene expression causing the transition of cells in the development of MVD in cavaliers.
- August 2015 - US researchers determine that only computed tomography (CT) can reliably detect non-bulging PSOM in cavaliers.
- August 2015 - Cavalier in congestive heart failure suffers blood clots, a tear in the left atrium wall, and a cardiac stroke.
- August 2015 - Belgium researchers find CT can be used to diagnose SM in dogs.
- August 2015 - UK researchers opine that corneal ulcers in cavaliers may be due to the breed standard favoring large eyes.
- July 2015 - Fortekor Plus -- combination of benazepril and pimobendan -- gets a green light in Europe.
- July 2015 - French researchers find cavaliers highly represented in study of idiopathic labial and facial canine vestibular neuropathy.
- July 2015 - Chinese researchers heal dogs' cataracts with lanosterol.
- July 2015 - Cavaliers were among 14 breeds found overweight in study of Crufts winners.
- July 2015 - Univ. of Minnesota pathologists report more breeds with the CKCS giant platelet disorder.
- July 2015 - Swedish vet student reports the cavalier has a high incidence of kidney disease in Sweden.
- July 2015 - Shocking survey of UK vets on treatment of CKCS in heart failure is very troubling.
- July 2015 -- Spanish study shows anticonvulsants may cause increase in canine pancreas-specific lipase but not acute pancreatitis.
- July 2015 - NEW WEBPAGE: Pyometra in the Cavalier King Charles Spaniel.
- July 2015 - OUR BLOG: Heart failure in the MVD-affected cavalier King Charles spaniel.
- June 2015 - NEW WEBPAGE: Vestibular Disorders and the Cavalier King Charles Spaniel.
- June 2015 - US researchers study microRNAs as possible biomarkers of MVD progression.
Veterinary specialists have designed breeding guidelines to eliminate early-onset mitral valve disease in cavalier King Charles spaniels.
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Syringomyelia (SM) is reported to be "very widespread" in the cavalier King Charles spaniel breed. Syringomyelia is a disorder of the brain and spinal cord, which may cause severe head and neck pain and possible paralysis.
- More: CKCS syringomyelia
- SM breeding protocol
- Research news
- Reduced rate MRI clinic locations
- MRI screening protocol for SM
- Find a neurologist in the USA and Canada
- Estimated Breeding Values (EBVs)
- "Pedigree Dogs Exposed"
- "Pedigree Dogs Exposed - Three Years On"
Hip dysplasia reportedly afflicts up to one out of every four cavalier King Charles spaniels. It is a genetic disease which can cause the dogs pain and debilitation.
Low blood platelet counts in cavaliers usually are not a health problem. Many veterinarians are misled by low platelet counts to wrongly diagnose anemia or other serious disorders.
The size and shape of its head can cause serious breathing problems for the cavalier King Charles spaniel. Elongated soft palates, stenotic nares, everted laryngeal saccules, and laryngeal collapse are inherited developmental defects in the breed.
Cavalier King Charles spaniels appear predisposed to develop cerebellar infarcts, or strokes.
Cavaliers are predisposed to a form of congenital deafness, which is present at birth, and also to a progressive hereditary hearing loss, which usually begins during puppyhood and worsens, or progresses, until the dog is completely deaf, usually between the ages of three and five years.
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