Heart mitral valve disease (MVD) is a terminal illness which may afflict over half of all cavalier King Charles spaniels by the age of 5 years and nearly all Cavaliers by age 10 years. It is CKCSs' leading cause of death.
- More: Cavalier King Charles spaniel MVD
- Mitral valve disease breeding protocol
- A few words about pimobendan (Vetmedin)
- ACVIM cardiologists consensus statement
- Research news
- NEW WEBPAGE: Chronic ulcerative paradental stomatitis (CUPS) and the CKCS.
- NEW WEBPAGE: Degenerative myelopathy and the cavalier King Charles spaniel.
- International study confirms the obvious: the louder the murmur, the worse the MVD.
- NEW WEBPAGE: Miscellaneous, for those other cavalier disorders you keep asking about!
- Survey of 2,000+ breeders shows half (wisely) do not trust veterinarians for nutrition advice.
- UK vets find follicular cystititis in a cavalier.
- Serotonin study shows concentration highest in cavaliers, with or without mitral valve disease.
- Study of 84 American Brussels Griffons finds syringomyelia and Chiari-like malformation to be prevalent.
- North Carolina State veterinarians make progress in stem cell therapy for damaged heart tissue.
- International team of cardiologists find cavaliers have higher serotonin concentrations in platelets.
- Thailand researchers find no difference in serotonin concentrations between healthy dogs and those with MVD, but ...
- UK researchers find two aspects of cavalier skull conformation are associated with the development of SM.
- Swedish researchers find high blood NT-proANP concentrations can predict onset of congestive heart failure within months.
- UK's Dr. Jacques Penderis finds MRI noise results in some hearing loss in dogs.
- UK's Royal Veterinary College seeks CKCSs for neuropathic pain assessment study.
- OUR BLOG: When NOT to start giving your cavalier pimobendan (Vetmedin).
- UK's Royal Veterinary College opens a clinic especially for brachycephalic dogs.
- OUR BLOG: Do-it-yourself diagnosing of congestive heart failure in your cavalier.
- UK cardiologist Simon Swift moves to University of Florida veterinary school.
- Brazil specialists find pimobendan improves clinical signs of MVD congestive heart failure, compared to digoxin.
- US neurologists find that high compression lesions due to thickened dural bands may relate to more severe pain and more severe syringomyelia in cavaliers.
- German researchers compare CKCSs with other breeds and find body weight can affect brain volumes, but no brain volume difference between CKCSs with and without SM.
- Japanese researchers find histamine concentration is higher in dogs with MVD.
- Texas A&M specialists report on PSOM case in a cavalier.
- Researchers find a link between high-level serotonin-binding and highly-activated blood platelets and mitral valve disease and oversized platelets in cavaliers.
- French researchers study 134 cavaliers and find their body weights affect echocardiographic interpretations.
- UK's Dogs Trust funds the search for genes for syringomyelia and painful Chiari-malformation in cavaliers.
- New dog genome research debunks evolutionist theory that dogs have adapted to carbohydrates.
- Italian investigator finds cavaliers' MVD is tied to chronic inflammation.
- Researchers identify two genomic regions associated with Chiari-like malformation (CM) in the Brussels Griffon.
- US study finds low serum vitamin D concentration is associated with poor outcomes of dogs with CHF.
- Epileptic CKCS has leg twitching and loss of muscle control reactions to potassium bromide treatment.
- German study of 107 CKCSs concurs that the causes of CM and SM are related to a growth disturbance of the cranial base.
- Danish study finds 15.4% CKCSs with symptomatic SM and progression from no symptoms to symptoms as late as after 6 years.
- NEW WEBPAGE: Cherry eye and the cavalier King Charles spaniel.
Veterinary specialists have designed breeding guidelines to eliminate early-onset mitral valve disease in cavalier King Charles spaniels.
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Syringomyelia (SM) is reported to be "very widespread" in the cavalier King Charles spaniel breed. Syringomyelia is a disorder of the brain and spinal cord, which may cause severe head and neck pain and possible paralysis.
- More: CKCS syringomyelia
- SM breeding protocol
- "Pedigree Dogs Exposed"
- "Pedigree Dogs Exposed - Three Years On"
- Estimated Breeding Values (EBVs)
- Research news
- Reduced rate MRI clinic locations
- MRI screening protocol for SM
Hip dysplasia reportedly afflicts up to one out of every four cavalier King Charles spaniels. It is a genetic disease which can cause the dogs pain and debilitation.
Low blood platelet counts in cavaliers usually are not a health problem. Many veterinarians are misled by low platelet counts to wrongly diagnose anemia or other serious disorders.
The size and shape of its head can cause serious breathing problems for the cavalier King Charles spaniel. Elongated soft palates, stenotic nares, everted laryngeal saccules, and laryngeal collapse are inherited developmental defects in the breed.
Cavalier King Charles spaniels appear predisposed to develop cerebellar infarcts, or strokes.
Cavaliers are predisposed to a form of congenital deafness, which is present at birth, and also to a progressive hereditary hearing loss, which usually begins during puppyhood and worsens, or progresses, until the dog is completely deaf, usually between the ages of three and five years.
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